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Unit 10 Verify Activity 1. You take part in the annual Coney Island Polar Bear Plunge and jump into frigid ocean water. The blood vessels in your skin vasoconstrict and systemic vascular resistance increases. As a result, your MAP increases from 93 mmHg to 120 mmHg.

Describe in a few sentences the two types of autoregulatory mechanisms that will maintain your GFR at normal levels (180 L/day)

Unit 10 Verify Activity 2.

a) The renal clearance of glucose is normally zero. Write a sentence or two and explain why glucose is present in the urine of an unmanaged type 1 diabetic (type 1 diabetics can’t produce endogenous insulin).

c) Propose a mechanism for a drug to treat type 2 diabetes (elevated blood glucose levels).

Respiration BONUS Activity

Attached Files:

Instructions:

Enter your response in the write submission box.Do not upload a file or write in the comments box. Write thoughtfully and professionally, using proper grammar and spelling. Do not include a restatement of the prompts, or any identifying information in your response.

The due date is April 23rd by 11:59 PM.

Detailed instructions can be found here here – Alternative Formats

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Background:

You are working as an intern in a small biotechnology company that is trying to develop genetic engineering approaches to improve the ability of humans to swim under water without SCUBA equipment or other sources of oxygen. As a physiologist, you realize that this problem has already been solved by marine mammals and birds who are able to function under water for extended periods of time. You decide to do some background research on diving mammals and birds and prepare a list of possible strategies to present at the next research staff meeting.

Assignment:

State two possible strategies for enhancing the ability of humans to function under water without access to additional oxygen and briefly discuss why you think each strategy would be effective.

Resources (attached files):

  • BIO 203 lecture recording – Diving Mammals and Birds
    (~8 min; view before starting activity; level of difficulty = introductory)
  • Costa, D.P., Diving Physiology of Marine Vertebrates, in eLS. 2007, John Wiley & Sons, Ltd. (recommended reading; level of difficulty = intermediate)
  • Ponganis, P.J., Diving mammals. Compr Physiol, 2011. 1(1): p. 447-65.
    (recommended reading; level of difficulty = advanced)

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